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Hypoxia-selective antitumor agents. II: Electronic effects of 4-substituents on the mechanisms of cytotoxicity and metabolic stability of nitracrine derivativesWILSON, W. R; THOMPSON, L. H; ANDERSON, R. F et al.Journal of medicinal chemistry (Print). 1989, Vol 32, Num 1, pp 31-38, issn 0022-2623, 8 p.Article

Selective toxicity of nitracrine to hypoxic mammalian cells = Toxicité sélective de la nitracrine sur les cellules hypoxiques de mammifèresWILSON, W. R; DENNY, W. A; TWIGDEN, S. J et al.British journal of cancer. 1984, Vol 49, Num 2, pp 215-223, issn 0007-0920Article

EFFECT OF NITRACRINE (LEDAKRIN, C-283) AND ACTINOMYCIN D ON HETEROPOLYMER AND POLY A SYNTHESIS CATALYZED BY BACTERIAL RNA POLYMERASECIESIELSKA E; JAROS KAMINSKA B; SLASKA K et al.1979; STUD. BIOPHYS.; DDR; DA. 1979; VOL. 73; NO 2; PP. 141-146; ABS. RUS; BIBL. 6 REF.Article

CYTOTOXICITY AND THE EFFECT OF COMBINED TREATMENT WITH X-RAYS OF AN ANTICANCER 1-NITRO-9-AMINOACRIDINE DERIVATIVE IN L5178Y-R AND L5178Y-S CELLSSZUMIEL I; WALICKA M.1980; NEOPLASMA; ISSN 0028-2685; CSK; DA. 1980; VOL. 27; NO 6; PP. 697-702; BIBL. 13 REF.Article

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Frameshift mutations induced by four isomeric nitroacridines and their des-nitro counterpart in the lacz reversion assay in escherichia coliHOFFMANN, George R; YIN, Catherine C; TERRY, Caitlin E et al.Environmental and molecular mutagenesis (Print). 2006, Vol 47, Num 2, pp 82-94, issn 0893-6692, 13 p.Article

DNA damage in HeLa S3 cells by an antitumor drug ledakrin and other antitumor 1-nitro-9-aminoacridinesWOYNAROWSKI, J. M; BARTOSZEK, A; KONOPA, J et al.Chemico-biological interactions. 1984, Vol 49, Num 3, pp 311-328, issn 0009-2797Article

EARLY EFFECT OF LEDAKRIN (A NITRO-DERIVATIVE OF ACRIDINE) ON CELL MEMBRANEPOPOWICZ P; PODSIALO H; KNAPOWSKI J et al.1980; ACTA PHYSIOL. POLON.; POL; DA. 1980; VOL. 31; NO 1; PP. 81-91; BIBL. 39 REF.Article

Mutagenic activity of nitracrine derivatives in Salmonella typhimurium: relationship to drug physicochemical parameters, and to bacterial uvrB and recA genes and plasmid pKM101FERGUSON, L. R; DENNY, W. A; O'ROURKE, S. M et al.Mutation research. 1989, Vol 223, Num 1, pp 13-22, issn 0027-5107Article

Are lethal effects of nitrarine on L5178Y cell sublines associated with DNA-protein crosslinks ?WALICKA, M; SZMIGIERO, L; CIESIELSKA, E et al.Biochemical pharmacology. 1993, Vol 46, Num 4, pp 615-620, issn 0006-2952Article

Mutagenic, recombinogenic and antimitochondrial effects of nitracrine analogues in Saccharomyces cerevisiaeFERGUSON, L. R; TURNER, P. M.Mutation research. 1987, Vol 187, Num 4, pp 209-217, issn 0027-5107Article

In vitro binding of nitracrine to DNA in chromatinWILMANSKA, D; SZMIGIERO, L; GNIAZDOWSKI, M et al.Zeitschrift für Naturforschung. C. A journal of biosciences. 1989, Vol 44, Num 3-4, pp 307-311, issn 0939-5075, 5 p.Article

Comparison of antitumor properties of nitracrine and amsacrine analogsMAZERSKA, Z; CHOŁODY, M; ŁUKOWICZ, J et al.Arzneimittel-Forschung. 1987, Vol 37, Num 11, pp 1276-1281, issn 0004-4172Article

Effect of intercalating and groove-binding ligands on formation of covalent complexes between nitracrine (Ledakrin, C-283) or 8-methoxypsoralen and DNAWILMANSKA, D; MAŁAGOCKA, E; SZMIGIERO, L et al.Biochimica et biophysica acta. 1984, Vol 782, Num 3, pp 285-294, issn 0006-3002Article

Design, synthesis and antiproliferative activity of novel aminosubstituted benzothiopyranoisoindolesCHRISTODOULOU, Antonios; KOSTAKIS, Ioannis K; KOURAFALOS, Vassilios et al.Bioorganic & medicinal chemistry letters (Print). 2011, Vol 21, Num 10, pp 3110-3112, issn 0960-894X, 3 p.Article

Acridine derivatives as chemotherapeutic agentsDENNY, William A.Current medicinal chemistry. 2002, Vol 9, Num 18, pp 1655-1665, issn 0929-8673Article

³²P-post-labeling analysis of DNA adduct formation by antitumor drug nitracrine (ledakrin) and other nitroacridines in different biological systemsBARTOSZEK, A; KONOPA, J.Biochemical pharmacology. 1989, Vol 38, Num 8, pp 1301-1312, issn 0006-2952Article

Synthesis and antiproliferative activity of substituted benzopyranoisoindoles : A new class of cytotoxic compoundsHADJIPAVLOU, Christiana; KOSTAKIS, Ioannis K; POULI, Nicole et al.Bioorganic & medicinal chemistry letters (Print). 2006, Vol 16, Num 18, pp 4822-4825, issn 0960-894X, 4 p.Article

Surface-enhanced Raman spectroscopic study of amsacrine and amsacrine-DNA interactionsBARTON, T. F; COONEY, R. P; DENNY, W. A et al.Journal of Raman spectroscopy. 1992, Vol 23, Num 6, pp 341-345, issn 0377-0486Article

QSAR of acridines. II, Features of nitracrine analogs for high anti-tumor activity and selectivity on mice, searched by PCA and MRA methodsMAZERSKA, Z; MAZERSKI, J; LEDOCHOWSKI, A et al.Anti-cancer drug design. 1990, Vol 5, Num 2, pp 169-187, issn 0266-9536Article

Effect of substituents on the metabolism of nitracrine in ratROBERTSON, I. G. C; BLAND, T. J; PALMER, B. D et al.Xenobiotica (London. Print). 1996, Vol 26, Num 5, pp 559-570, issn 0049-8254, 11 p.Article

Nitracrine and its congeners : an overviewGNIAZDOWSKI, M; SZMIGIERO, L.General pharmacology. 1995, Vol 26, Num 3, pp 473-481, issn 0306-3623Article